Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573984 | 0.84 | CRHBP (0.50) | MAPK1ALDH1A1MAPTNPSR1CRHBP | |
| SCHEMBL9029961 | 0.83 | KMT2A (0.48) | MEN1KMT2AL3MBTL1MAPK1TDP1 | |
| SCHEMBL9030000 | 0.81 | MAPT (0.47) | MEN1KMT2AL3MBTL1MAPK1TDP1 | |
| SCHEMBL7574989 | 0.80 | RAB9A (0.61) | MEN1KMT2AMAPK1ALDH1A1MAPT | |
| SCHEMBL24202473 | 0.79 | ALDH1A1 (0.62) | MEN1KMT2AL3MBTL1MAPK1TDP1 | |
| SCHEMBL7419391 | 0.79 | ALDH1A1 (0.62) | MEN1KMT2AL3MBTL1MAPK1TDP1 | |
| SCHEMBL31722182 | 0.79 | ALDH1A1 (0.62) | MEN1KMT2AL3MBTL1MAPK1TDP1 | |
| SCHEMBL1985402 | 0.79 | ALDH1A1 (0.62) | MEN1KMT2AL3MBTL1MAPK1TDP1 | |
| SCHEMBL27791616 | 0.79 | MEN1 (0.53) | MEN1KMT2AL3MBTL1MAPK1TDP1 | |
| SCHEMBL6404329 | 0.79 | CYP1A2 (0.55) | MEN1KMT2AL3MBTL1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |