Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.54 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573365 | 0.87 | MAPT (0.61) | RAB9ANPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7573984 | 0.82 | CRHBP (0.50) | MAPTMAPK1ALDH1A1CRHBPCRHR2 | |
| SCHEMBL7576552 | 0.80 | MEN1 (0.51) | RAB9ANPC1MAPTMAPK1MEN1 | |
| SCHEMBL29160955 | 0.79 | RAB9A (0.56) | RAB9ANPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL14764687 | 0.79 | MEN1 (0.57) | RAB9ANPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL29160956 | 0.79 | RAB9A (0.56) | RAB9ANPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL2488724 | 0.78 | KMT2A (0.57) | RAB9ANPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL13240813 | 0.78 | KMT2A (0.57) | RAB9ANPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7583883 | 0.78 | LMNA (0.58) | MAPTSMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL3322365 | 0.78 | MAPT (0.56) | RAB9ANPC1MAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |