Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5418178 | 0.89 | ELANE (0.39) | ELANEKDM4ETSHRKMT2AATM | |
| SCHEMBL28807130 | 0.87 | ELANE (0.38) | ELANEKDM4EKMT2AATMTDP1 | |
| SCHEMBL28465620 | 0.85 | KDM4E (0.43) | KDM4ETSHRCYP3A4KMT2ATDP1 | |
| SCHEMBL10870368 | 0.84 | KDM4E (0.49) | ELANEKDM4ETSHRCYP3A4KMT2A | |
| SCHEMBL27434188 | 0.84 | KDM4E (0.49) | ELANEKDM4ETSHRCYP3A4KMT2A | |
| SCHEMBL10632078 | 0.84 | ELANE (0.36) | ELANEKDM4EKMT2ATDP1POLB | |
| SCHEMBL10445306 | 0.83 | KDM4E (0.55) | ELANEKDM4ETSHRCYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL5582116 | 0.82 | KDM4E (0.54) | ELANEKDM4ETSHRCYP3A4KMT2A | |
| SCHEMBL3440798 | 0.82 | THRB (0.46) | ELANEKDM4ETSHRCYP3A4KMT2A | |
| SCHEMBL15495926 | 0.82 | ALDH1A1 (0.48) | ELANEKDM4ETSHRCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178770-A1 | DENTAL MATERIALS | 3M Innovative Properties Company (US) | 2002-02-13 | — | — | EP | claimed |
| WO-2000069395-A1 | DENTAL MATERIALS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-11-23 | — | — | WO | claimed |