SCHEMBL28465620

SCHEMBL28465620

C=C(C)C(=O)OC(C)Oc1ccc(C(CC)c2ccc(OC(C)OC(=O)C(=C)C)cc2OCC)c(OCC)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
HIF1A Q16665 1/20 0.37
PTGS2 P35354 1/20 0.37
LMNA P02545 2/20 0.36
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
ACACB O00763 2/20 0.35
ACACA Q13085 2/20 0.35
ALDH1A1 P00352 1/20 0.34
EPHX1 P07099 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MAPT P10636 1/20 0.34
APEX1 P27695 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7576563 0.85 ELANE (0.43) KDM4EAKR1C3AKR1C2HIF1APTGS2
SCHEMBL28563446 0.83 KDM4E (0.40) KDM4EAKR1C3AKR1C2HIF1APTGS2
SCHEMBL20394026 0.82 KDM4E (0.42) KDM4EAKR1C3AKR1C2HIF1ALMNA
SCHEMBL28552774 0.82 KDM4E (0.42) KDM4EAKR1C3AKR1C2HIF1ALMNA
SCHEMBL6271214 0.80 L3MBTL1 (0.35) KDM4ELMNATSHRALDH1A1TDP1
SCHEMBL4651421 0.79 ALDH1A1 (0.39) AKR1C3AKR1C2HIF1ATSHRACACB
SCHEMBL5418178 0.77 ELANE (0.39) KDM4EAKR1C3AKR1C2HIF1APTGS2
SCHEMBL7564773 0.77 ELANE (0.41) TSHRALDH1A1TDP1CYP1A2KMT2A
SCHEMBL28443934 0.76 PTGS1 (0.40) KDM4ELMNAALDH1A1MEN1KMT2A
SCHEMBL28807130 0.75 ELANE (0.38) KDM4EHIF1AALDH1A1TDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689698-B Polymerizable composition for optical material and molded article 三井化学株式会社 2022-05-31 CN disclosed
CN-113993905-A Method for setting use condition of polymerization catalyst, method for setting polymerization condition, and method for producing optical material 三井化学株式会社 2022-01-28 CN disclosed
CN-107949584-B Polymerizable composition for optical material, optical material obtained from the composition, and plastic lens 三井化学株式会社 2021-04-27 CN disclosed
CN-111868099-A Method for setting polymerization conditions and method for producing optical material 三井化学株式会社 2020-10-30 CN disclosed