Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569876 | 0.87 | FAAH (0.39) | ALDH1A1L3MBTL1TDP1SMN1; SMN2NPC1 | |
| SCHEMBL7571120 | 0.87 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1TDP1SMN1; SMN2NPC1 | |
| SCHEMBL7573230 | 0.86 | TSHR (0.45) | ALDH1A1L3MBTL1TDP1SMN1; SMN2NPC1 | |
| SCHEMBL8599745 | 0.86 | ESR1 (0.39) | ALDH1A1L3MBTL1TDP1SMN1; SMN2NPC1 | |
| SCHEMBL6448597 | 0.83 | SLC6A2 (0.40) | POLBALDH1A1L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL7570466 | 0.83 | MAPT (0.45) | ALDH1A1L3MBTL1TDP1MAPTGAA | |
| SCHEMBL7570565 | 0.83 | ALDH1A1 (0.47) | POLBALDH1A1L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL7570460 | 0.82 | TSHR (0.37) | ALDH1A1L3MBTL1TDP1SMN1; SMN2NPC1 | |
| SCHEMBL7567342 | 0.80 | CETP (0.40) | POLBALDH1A1L3MBTL1TDP1SMN1; SMN2 | |
| SCHEMBL6136368 | 0.79 | HTT (0.41) | POLBALDH1A1TDP1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |