Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7227154 | 0.84 | FSCN1 (0.46) | ALDH1A1TDP1L3MBTL1FSCN1MAPK1 | |
| SCHEMBL7576950 | 0.83 | POLB (0.40) | ALDH1A1TDP1L3MBTL1CNR1KMT2A | |
| SCHEMBL6136395 | 0.81 | FSCN1 (0.53) | ALDH1A1TDP1L3MBTL1FSCN1RAB9A | |
| SCHEMBL8599745 | 0.80 | ESR1 (0.39) | ALDH1A1TDP1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL7571655 | 0.77 | TSHR (0.42) | ALDH1A1TDP1L3MBTL1MAPK1ESR1 | |
| SCHEMBL7576541 | 0.76 | TSHR (0.41) | ALDH1A1TDP1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL7573230 | 0.75 | TSHR (0.45) | ALDH1A1TDP1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL7570460 | 0.73 | TSHR (0.37) | ALDH1A1TDP1L3MBTL1MAPK1ESR1 | |
| SCHEMBL7571120 | 0.73 | ALDH1A1 (0.39) | ALDH1A1TDP1L3MBTL1MAPK1ESR1 | |
| SCHEMBL7569876 | 0.73 | FAAH (0.39) | ALDH1A1TDP1L3MBTL1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |