Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587452 | 0.90 | MAPT (0.43) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL16369913 | 0.72 | HTR6 (0.59) | HTR6AKR1B1ALDH1A1NPSR1MAPT | |
| SCHEMBL16369859 | 0.70 | MEN1 (0.54) | HTR6AKR1B1MEN1KMT2A | |
| SCHEMBL628152 | 0.69 | MEN1 (0.50) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL1274804 | 0.67 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL7068509 | 0.67 | HTR6 (0.45) | HTR6ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL5609096 | 0.67 | HTR6 (0.46) | HTR6AKR1B1ALDH1A1MEN1KMT2A | |
| (Phenylsulfonyl)Benzene SCHEMBL2148473 | 0.66 | HTR6 (0.82) | HTR6ALDH1A1MAPTTDP1HSD17B10 | |
| SCHEMBL19846079 | 0.66 | HSD11B1 (0.48) | HTR6AKR1B1MEN1KMT2APIK3CA | |
| SCHEMBL10354233 | 0.65 | HTR6 (0.62) | HTR6AKR1B1ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100864-A1 | PYRAZOLOPYRAZINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-19 | — | — | WO | disclosed |