Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | PGK1 | P00558 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570115 | 0.86 | RAB9A (0.52) | CYP3A4CYP1A2CYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL7572481 | 0.85 | HTT (0.54) | CYP3A4CYP1A2CYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL7572173 | 0.78 | FNTA (0.50) | — | |
| SCHEMBL6982380 | 0.76 | NR1D1 (0.44) | — | |
| SCHEMBL7423977 | 0.76 | MAPT (0.56) | CYP3A4CYP1A2CYP2C19CYP2C9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7567497 | 0.76 | NR1D1 (0.44) | — | |
| SCHEMBL7085038 | 0.76 | FNTA (0.47) | — | |
| SCHEMBL22530409 | 0.75 | ALDH1A1 (0.55) | CYP3A4CYP1A2CYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL10558180 | 0.72 | CYP3A4 (0.68) | CYP3A4CYP1A2CYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL5714168 | 0.71 | ALDH1A1 (0.64) | CYP3A4CYP1A2CYP2C19ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | CYP3A4 269/4885CYP1A2 276/4885CYP2C19 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.