Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PGK1 | P00558 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558180 | 0.77 | CYP3A4 (0.68) | MAPTMEN1KMT2APABPC1LTA4H | |
| SCHEMBL5714168 | 0.77 | ALDH1A1 (0.64) | MAPTMEN1KMT2APABPC1LTA4H | |
| SCHEMBL10814853 | 0.76 | KDM4C (0.60) | MAPTMEN1KMT2APABPC1LTA4H | |
| SCHEMBL7577205 | 0.76 | CYP3A4 (0.57) | MAPTMEN1KMT2APABPC1LTA4H | |
| SCHEMBL6730573 | 0.75 | LTA4H (0.72) | MAPTMEN1KMT2APABPC1LTA4H | |
| SCHEMBL6732492 | 0.75 | LTA4H (0.66) | MAPTMEN1KMT2APABPC1LTA4H | |
| SCHEMBL10814098 | 0.74 | ALDH1A1 (0.59) | MAPTMEN1KMT2APABPC1LTA4H | |
| SCHEMBL10812477 | 0.74 | LTA4H (0.56) | MAPTMEN1KMT2APABPC1LTA4H | |
| SCHEMBL10813207 | 0.73 | LTA4H (0.52) | MAPTMEN1KMT2APABPC1LTA4H | |
| SCHEMBL19190687 | 0.73 | RAB9A (0.52) | MAPTMEN1KMT2APABPC1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255735-A2 | PYRIDINE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001056990-A2 | PYRIDINE DERIVATES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |