SCHEMBL7577244

SCHEMBL7577244

CCOc1cccc(-c2ccccc2)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
L3MBTL1 Q9Y468 3/20 0.51
ADORA3 P0DMS8 1/20 0.48
ADORA2A P29274 1/20 0.48
ADORA1 P30542 1/20 0.48
GLA P06280 1/20 0.47
PDK2 Q15119 1/20 0.47
ADRB2 P07550 1/20 0.45
HNF4A P41235 1/20 0.44
HPGD P15428 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MAPT P10636 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HTR7 P34969 1/20 0.44
F2 P00734 1/20 0.43
F10 P00742 1/20 0.43
PLG P00747 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4744929 0.84 TP53 (0.51) ALDH1A1ADRB2HNF4AHDAC4HDAC2
SCHEMBL29290124 0.84 ALDH1A1 (0.49) ALDH1A1L3MBTL1ADORA3ADORA2AADORA1
SCHEMBL203121 0.83 ADRB2 (0.61) ALDH1A1L3MBTL1ADORA3ADORA2AADORA1
SCHEMBL9257290 0.82 THRA (0.53) ALDH1A1ADRB2MAPTHDAC6HTR7
SCHEMBL9123358 0.82 THRA (0.53) ALDH1A1ADRB2MAPTHDAC6HTR7
SCHEMBL4744927 0.82 MEN1 (0.48) ALDH1A1L3MBTL1GLAPDK2HPGD
Phenol SCHEMBL27639588 0.82 ADRB2 (0.53) ALDH1A1L3MBTL1GLAADRB2HPGD
Fluoride SCHEMBL27432507 0.81 ADRB2 (0.59) ALDH1A1L3MBTL1ADORA3ADORA2AADORA1
Propane SCHEMBL27542299 0.81 ADRB2 (0.59) ALDH1A1L3MBTL1ADORA3ADORA2AADORA1
SCHEMBL27377174 0.81 RXRA (0.56) L3MBTL1TDP1MAPTHDAC6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1214289-A1 MULTIDENTATE PHOSPHITE LIGANDS AND CATALYTIC COMPOSITIONS CONTAINING SAME E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-06-19 EP disclosed
WO-2001021579-A1 MULTIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING SUCH LIGANDS AND CATALYTIC PROCESSES UTILIZING SUCH CATALYTIC COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-03-29 WO disclosed