Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576816 | 0.79 | ADRA2A (0.43) | TAAR1DRD2 | |
| SCHEMBL2147997 | 0.70 | CYP2D6 (0.37) | — | |
| SCHEMBL16543102 | 0.70 | TAAR1 (0.41) | TAAR1HTR1ADRD2HTR7SIGMAR1 | |
| SCHEMBL7551810 | 0.70 | DRD2 (0.40) | DRD2 | |
| SCHEMBL7586414 | 0.70 | DRD2 (0.40) | DRD2 | |
| SCHEMBL12285519 | 0.69 | — | — | |
| SCHEMBL14029671 | 0.69 | KDM4C (0.45) | — | |
| SCHEMBL8578128 | 0.68 | MAOA (0.34) | — | |
| SCHEMBL12891560 | 0.68 | TAAR1 (0.44) | TAAR1HTR1ADRD2HTR7SIGMAR1 | |
| SCHEMBL12891564 | 0.68 | TAAR1 (0.44) | TAAR1HTR1ADRD2HTR7SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | ABBOTT LABORATORIES | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | NQO2, NQO1, NDUFA7 | TAAR1 2464/4885HTR1A 2551/4885DRD2 2325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.