Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551810 | 0.88 | DRD2 (0.40) | DRD2DRD3GRIN2B | |
| SCHEMBL7580734 | 0.86 | NOS2 (0.34) | DRD2DRD3 | |
| SCHEMBL3806985 | 0.77 | PLAU (0.41) | GRIN2B | |
| SCHEMBL7608832 | 0.76 | DRD2 (0.48) | DRD2DRD3GRIN2B | |
| SCHEMBL23364990 | 0.72 | CYP2C9 (0.40) | — | |
| SCHEMBL432585 | 0.71 | — | — | |
| SCHEMBL428179 | 0.70 | TRPV1 (0.36) | DRD2DRD3 | |
| SCHEMBL7577546 | 0.70 | TAAR1 (0.38) | DRD2 | |
| SCHEMBL21831999 | 0.70 | DAPK3 (0.38) | DRD2DRD3 | |
| SCHEMBL16286105 | 0.70 | DPP4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | ABBOTT LABORATORIES | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | NQO2, NQO1, NDUFA7 | DRD2 2325/4885DRD3 2620/4885GRIN2B 3775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.