Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.64 |
| ▸ | CCR2 | P41597 | 4/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | ACLY | P53396 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CCR4 | P51679 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4191121 | 0.81 | PTGES2 (0.69) | PTGES2CCR2PGRACLYMAPT | |
| SCHEMBL5694587 | 0.81 | PTGES2 (0.69) | PTGES2CCR2PGRACLYMAPT | |
| SCHEMBL2516364 | 0.80 | MCOLN3 (0.68) | PTGES2CCR2PGRACLYMAPT | |
| SCHEMBL7579053 | 0.79 | PGR (0.75) | PTGES2PGRMAPTALDH1A1LMNA | |
| SCHEMBL7589760 | 0.79 | CCR2 (0.59) | PTGES2CCR2ACLYALDH1A1LMNA | |
| SCHEMBL3773868 | 0.78 | PTGES2 (1.00) | PTGES2 | |
| SCHEMBL7577515 | 0.78 | SMN1; SMN2 (0.65) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL13146531 | 0.78 | PGR (0.67) | PTGES2CCR2PGRACLYCYP1A2 | |
| SCHEMBL7594240 | 0.78 | CCR2 (0.57) | PTGES2CCR2CCR4MEN1KMT2A | |
| SCHEMBL34475240 | 0.77 | MEN1 (0.78) | PTGES2CCR2ACLYALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |