Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | ACLY | P53396 | 1/20 | 0.74 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | CCR2 | P41597 | 5/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CCR4 | P51679 | 2/20 | 0.65 |
| ▸ | CCR5 | P51681 | 2/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770307 | 0.91 | MEN1 (0.78) | MEN1KMT2ALMNAACLYSLC25A1 | |
| SCHEMBL3088122 | 0.88 | KMT2A (0.62) | MEN1KMT2ALMNAACLYSLC25A1 | |
| SCHEMBL10695037 | 0.88 | MEN1 (0.73) | MEN1KMT2ALMNAACLYSLC25A1 | |
| SCHEMBL21999967 | 0.85 | ACLY (1.00) | ACLY | |
| SCHEMBL643467 | 0.85 | LMNA (0.66) | MEN1KMT2ALMNAACLYSLC25A1 | |
| SCHEMBL492000 | 0.84 | ACLY (0.72) | ACLYCCR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3089865 | 0.84 | ACLY (0.73) | MEN1KMT2ALMNAACLYSLC25A1 | |
| SCHEMBL30000258 | 0.84 | SLC25A1 (1.00) | MEN1KMT2ALMNAACLYSLC25A1 | |
| SCHEMBL29918322 | 0.84 | SLC25A1 (1.00) | MEN1KMT2ALMNAACLYSLC25A1 | |
| SCHEMBL30777865 | 0.84 | SLC25A1 (1.00) | MEN1KMT2ALMNAACLYSLC25A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026088050-A1 | SMALL MOLECULE INHIBITOR OF FOXA1 AND FOXA2 FOR THE TREATMENT OF FOXA1/FOXA2-DEPENDENT CANCERS OR OTHER DISEASES | FONDAZIONE PER L'ISTITUTO ONCOLOGICO DI RICERCA (IOR) (CH) | 2026-04-30 | — | — | WO | disclosed |