SCHEMBL7578702

SCHEMBL7578702

COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)O)n1.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32
CCR6 P51684 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 1/20 0.32
KDM4E B2RXH2 3/20 0.31
HSP90AA1 P07900 1/20 0.31
ACLY P53396 1/20 0.31
PKM P14618 1/20 0.30
PTGER4 P35408 1/20 0.30
GAA P10253 1/20 0.30
SLC40A1 Q9NP59 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorsulfuron SCHEMBL7580466 0.95 NPC1 (0.35) KMT2AMEN1MAPTNPSR1L3MBTL1
Iodosulfuron SCHEMBL7581973 0.94 MEN1 (0.31) KMT2AMEN1MAPTNPSR1L3MBTL1
Logran SCHEMBL7586300 0.93 KMT2A (0.33) KMT2AMEN1MAPTNPSR1L3MBTL1
Prosulfuron SCHEMBL7589175 0.92 KMT2A (0.33) KMT2AMEN1MAPTNPSR1L3MBTL1
SCHEMBL7578757 0.92 MEN1 (0.31) KMT2AMEN1MAPTNPSR1L3MBTL1
SCHEMBL7585330 0.91 KDM4E (0.36) KMT2AMEN1MAPTNPSR1L3MBTL1
SCHEMBL7580518 0.91 KMT2A (0.32) KMT2AMEN1MAPTNPSR1L3MBTL1
SCHEMBL7577344 0.89 KDM4E (0.34) KMT2AMEN1MAPTLMNANPC1
Acifluorfen SCHEMBL7584724 0.86 KMT2A (0.45) KMT2AMEN1MAPTNPSR1L3MBTL1
Flupyrsulfuron SCHEMBL7581065 0.85 GAA (0.32) KMT2AMEN1MAPTNPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KMT2A 2099/4885MEN1 4274/4885MAPT 1092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.