Flupyrsulfuron

Flupyrsulfuron

SCHEMBL7581065

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2nc(C(F)(F)F)ccc2C(=O)O)n1.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.32
KMT2A Q03164 3/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HSP90AA1 P07900 1/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32
CCR6 P51684 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
PKM P14618 1/20 0.31
MALT1 Q9UDY8 1/20 0.31
SLC40A1 Q9NP59 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7593637 0.90 L3MBTL1 (0.33) GAAKMT2AL3MBTL1MEN1MAPT
Flupyrsulfuron SCHEMBL7588713 0.88 GAA (0.41) GAAKMT2AMEN1
Sulfosulfuron SCHEMBL7588923 0.86 NPC1 (0.30) KMT2ANPC1RAB9A
Flupyrsulfuron SCHEMBL7582658 0.85 KMT2A (0.46) GAAKMT2AL3MBTL1MEN1MAPT
Flupyrsulfuron SCHEMBL7578529 0.85 KMT2A (0.35) GAAKMT2AL3MBTL1MEN1MAPT
SCHEMBL7578702 0.85 KMT2A (0.32) GAAKMT2AL3MBTL1MEN1MAPT
Flupyrsulfuron SCHEMBL7576791 0.84 KMT2A (0.41) GAAKMT2AL3MBTL1MEN1MAPT
Iodosulfuron SCHEMBL7581973 0.84 MEN1 (0.31) KMT2AL3MBTL1MEN1MAPTNPSR1
Chlorsulfuron SCHEMBL7580466 0.83 NPC1 (0.35) GAAKMT2AL3MBTL1MEN1MAPT
Flupyrsulfuron SCHEMBL7582327 0.83 MEN1 (0.42) GAAKMT2AL3MBTL1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT GAA 288/4885KMT2A 2099/4885L3MBTL1 2160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.