SCHEMBL7585330

SCHEMBL7585330

CCOc1nc(NC)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)O)n1.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 2/20 0.36
NPC1 O15118 2/20 0.36
MAPT P10636 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.32
KMT2A Q03164 3/20 0.32
RAB9A P51151 1/20 0.32
PKM P14618 1/20 0.32
MEN1 O00255 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
HSP90AA1 P07900 1/20 0.31
LMNA P02545 1/20 0.31
ALOX12 P18054 1/20 0.31
CCR6 P51684 1/20 0.31
ACLY P53396 1/20 0.31
GAA P10253 1/20 0.30
SLC40A1 Q9NP59 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7578702 0.91 KMT2A (0.32) KDM4EALDH1A1NPC1MAPTKMT2A
SCHEMBL7583954 0.90 ALDH1A1 (0.44) KDM4EALDH1A1NPC1MAPTSMN1; SMN2
Chlorsulfuron SCHEMBL7580466 0.86 NPC1 (0.35) KDM4EALDH1A1NPC1MAPTKMT2A
Acifluorfen SCHEMBL7580076 0.86 KMT2A (0.45) KDM4EALDH1A1NPC1MAPTSMN1; SMN2
Oxyfluorfen SCHEMBL7585570 0.85 KMT2A (0.41) KDM4EALDH1A1NPC1MAPTSMN1; SMN2
Iodosulfuron SCHEMBL7581973 0.85 MEN1 (0.31) KDM4EMAPTKMT2AMEN1NPSR1
Logran SCHEMBL7586300 0.84 KMT2A (0.33) KDM4ENPC1MAPTKMT2ARAB9A
Aclonifen SCHEMBL7577886 0.83 NPC1 (0.39) KDM4EALDH1A1NPC1MAPTSMN1; SMN2
Fomesafen SCHEMBL7578836 0.83 KMT2A (0.41) KDM4EALDH1A1NPC1MAPTSMN1; SMN2
Prosulfuron SCHEMBL7589175 0.83 KMT2A (0.33) KDM4ENPC1MAPTKMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KDM4E 1886/4885ALDH1A1 812/4885NPC1 4238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.