Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.83 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.55 |
| ▸ | IL1RN | P18510 | 1/20 | 0.55 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27335781 | 0.88 | PKM (0.67) | PKMKEAP1IL1RNERAP1KMT2A | |
| SCHEMBL7572618 | 0.86 | PKM (0.70) | PKMKMT2AALDH1A1MEN1SLC40A1 | |
| SCHEMBL96565 | 0.83 | PKM (0.66) | PKMKEAP1IL1RNERAP1KMT2A | |
| SCHEMBL7569548 | 0.83 | PKM (0.66) | PKMKMT2AALDH1A1MEN1SLC40A1 | |
| SCHEMBL6073362 | 0.82 | CA1 (0.62) | PKMKEAP1IL1RNERAP1KMT2A | |
| SCHEMBL7595736 | 0.82 | SLC40A1 (0.61) | PKMSLC40A1CA1CA2 | |
| SCHEMBL28270280 | 0.80 | HTR6 (0.61) | PKMKMT2AMEN1SLC40A1POLB | |
| SCHEMBL29530798 | 0.80 | HTR6 (0.61) | PKMKMT2AMEN1SLC40A1POLB | |
| SCHEMBL22145982 | 0.80 | SLC40A1 (0.59) | PKMALDH1A1SLC40A1POLBCA1 | |
| SCHEMBL7163015 | 0.80 | ALDH1A1 (0.68) | PKMKEAP1IL1RNERAP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246028-A1 | QUINOLINE COMPOUNDS FOR INCREASING INSULINE RELEASE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-11-22 | — | — | EP | disclosed |
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |