Isoxaflutole

Isoxaflutole

SCHEMBL7579341

CCc1cccc(C)c1N(C(=O)CCl)C(C)COC.CS(=O)(=O)c1cc(C(F)(F)F)ccc1C(=O)c1cnoc1C1CC1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.37
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
THRB P10828 1/20 0.34
NR1I2 O75469 1/20 0.33
CACNA1B Q00975 1/20 0.33
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoxaflutole SCHEMBL8145509 1.00 MAPT (0.37) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Isoxaflutole SCHEMBL18115334 1.00 MAPT (0.37) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Isoxaflutole SCHEMBL19463328 0.88 THRB (0.50) THRBNR1I2CACNA1BDHODH
Isoxaflutole SCHEMBL17927171 0.88 THRB (0.50) THRBNR1I2CACNA1BDHODH
Isoxaflutole SCHEMBL7584184 0.87 MEN1 (0.31) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Isoxaflutole SCHEMBL7583603 0.87
Isoxaflutole SCHEMBL7582526 0.86 MEN1 (0.32) MAPTMEN1KMT2ATHRBTDP1
Oxyfluorfen SCHEMBL7588965 0.86 MEN1 (0.35) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
Isoxaflutole SCHEMBL7584845 0.86 MEN1 (0.43) ALDH1A1MEN1KMT2ASMN1; SMN2TDP1
Isoxaflutole SCHEMBL8147510 0.85 TP53 (0.49) ALDH1A1MEN1KMT2ANR1I2CACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3244742-A1 HERBICIDAL COMBINATION COMPRISING SAFLUFENACIL AND GLUFOSINATE BASF SE (DE) 2017-11-22 EP disclosed
WO-2016113334-A1 HERBICIDAL COMBINATION COMPRISING SAFLUFENACIL AND GLUFOSINATE BASF SE (DE) 2016-07-21 WO disclosed
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed
WO-2000003595-A1 COMPOSITIONS AND METHODS FOR PROTECTING CULTIVATED PLANTS FROM HERBICIDAL INJURY MICHIGAN STATE UNIVERSITY (US) 2000-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MAPT 1092/4885ALDH1A1 812/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.