Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 4/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 4/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498048 | 0.86 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7549698 | 0.82 | TPSAB1 (0.32) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7419360 | 0.78 | NAMPT (0.49) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7503667 | 0.74 | F2 (0.58) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7422920 | 0.74 | TPSAB1 (0.74) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7543760 | 0.73 | TPSAB1 (0.37) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7495608 | 0.68 | TPSAB1 (0.57) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL7443913 | 0.67 | TPSAB1 (0.61) | TPSAB1TPSD1TPSG1PRSS1F2 | |
| SCHEMBL4099538 | 0.65 | KMT2A (0.57) | ALDH1A1KDM4EPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL7424872 | 0.64 | TPSAB1 (0.53) | TPSAB1TPSD1TPSG1PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934293-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH TRYPTASE ACTIVITY | ARRIS PHARMACEUTICAL CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004537-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH TRYPTASE ACTIVITY | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |