Propaquizafop

Propaquizafop

SCHEMBL7579464

CC(C)=NOCCOC(=O)[C@@H](C)Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1.CCCCCOC(=O)COc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
NFKB1 P19838 1/20 0.39
HIF1A Q16665 1/20 0.39
GMNN O75496 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
APEX1 P27695 1/20 0.39
PMP22 Q01453 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
PPOX P50336 5/20 0.35
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flumiciorac-Pentyl SCHEMBL7581616 0.91 ALDH1A1 (0.41) ALDH1A1TP53CYP1A2CYP3A4ALOX15
Propaquizafop SCHEMBL7579648 0.88 TP53 (0.40) ALDH1A1TP53CYP1A2CYP3A4ALOX15
Flumiciorac-Pentyl SCHEMBL7575542 0.80 ALDH1A1 (0.38) ALDH1A1L3MBTL1TDP1PPOX
Propaquizafop SCHEMBL7583093 0.79 TP53 (0.38) ALDH1A1TP53CYP1A2CYP3A4ALOX15
Propaquizafop SCHEMBL7580397 0.79 TP53 (0.39) ALDH1A1TP53CYP1A2CYP3A4ALOX15
Propaquizafop SCHEMBL43925 0.78 MAPT (0.61) ALDH1A1TP53CYP1A2CYP3A4ALOX15
Propaquizafop SCHEMBL54333 0.78 MAPT (0.61) ALDH1A1TP53CYP1A2CYP3A4ALOX15
Propaquizafop SCHEMBL9136963 0.78 MAPT (0.61) ALDH1A1TP53CYP1A2CYP3A4ALOX15
Flumiciorac-Pentyl SCHEMBL7589562 0.78 L3MBTL1 (0.41) ALDH1A1L3MBTL1TDP1PPOXGAA
Flumiciorac-Pentyl SCHEMBL7588946 0.77 PPOX (0.39) ALDH1A1L3MBTL1TDP1PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT ALDH1A1 812/4885TP53 4303/4885CYP1A2 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.