Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702333 | 0.73 | KCNH2 (0.44) | LMNAKCNH2ALDH1A1 | |
| SCHEMBL7579693 | 0.72 | KCNH2 (0.45) | KDM4ECYP2B6KCNH2 | |
| SCHEMBL2424440 | 0.70 | LMNA (0.54) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL147711 | 0.69 | SLC6A2 (0.68) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL317556 | 0.68 | LMNA (0.69) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL8588185 | 0.68 | CHRM2 (0.53) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL7570154 | 0.68 | LMNA (0.55) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL7579685 | 0.68 | KDM4E (0.45) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL8579171 | 0.67 | CHRM2 (0.55) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL4454908 | 0.66 | GRIN1 (0.43) | MEN1KMT2ALMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020091139-A1 | Treatment and delivery of hydroxychloroquine | DAMON TODD HOLDINGS, L.L.C. | 2002-07-11 | — | — | US | disclosed |