Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702333 | 0.74 | KCNH2 (0.44) | KCNH2GRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL7579679 | 0.72 | CHRM2 (0.48) | KCNH2KDM4ECYP2B6 | |
| SCHEMBL6284917 | 0.68 | GRIN1 (0.44) | KCNH2GRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL4454908 | 0.67 | GRIN1 (0.43) | KCNH2GRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL12809670 | 0.65 | GRIN1 (0.42) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL705236 | 0.65 | GRIN1 (0.39) | KCNH2GRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL702749 | 0.65 | KCNH2 (0.37) | KCNH2GRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL10429856 | 0.64 | ADRA2A (0.43) | KCNH2KDM4EPGRADRA2AADRA2B | |
| SCHEMBL9778413 | 0.64 | CHRM2 (0.54) | KCNH2PGRADRA2AADRA2BHTR2A | |
| SCHEMBL416118 | 0.63 | GRIN1 (0.47) | KCNH2GRIN1GRIN2AGRIN2DGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020091139-A1 | Treatment and delivery of hydroxychloroquine | DAMON TODD HOLDINGS, L.L.C. | 2002-07-11 | — | — | US | disclosed |