Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363823 | 0.84 | CHRM2 (0.46) | KDM4ECHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL27541826 | 0.73 | MEN1 (0.35) | CYP1A2LMNACYP3A4MEN1KMT2A | |
| SCHEMBL8588185 | 0.71 | CHRM2 (0.53) | KDM4ECHRM2CHRM1CHRM3CYP2D6 | |
| SCHEMBL7579679 | 0.68 | CHRM2 (0.48) | KDM4ECHRM2CHRM1CHRM3CYP2D6 | |
| SCHEMBL2424440 | 0.67 | LMNA (0.54) | KDM4ECHRM2CHRM1CHRM3CYP2D6 | |
| SCHEMBL147711 | 0.66 | SLC6A2 (0.68) | KDM4ECHRM2CHRM1CHRM3CYP2D6 | |
| SCHEMBL16685441 | 0.66 | MEN1 (0.48) | LMNASMN1; SMN2MEN1KMT2APOLB | |
| Butetamate SCHEMBL1643343 | 0.66 | KDM4E (0.84) | KDM4ECHRM2CHRM1CHRM3CYP2D6 | |
| SCHEMBL8365387 | 0.66 | SIGMAR1 (0.38) | KDM4ECHRM2CHRM1CHRM3CYP2D6 | |
| SCHEMBL9161407 | 0.66 | LMNA (0.42) | CYP1A2LMNACYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020091139-A1 | Treatment and delivery of hydroxychloroquine | DAMON TODD HOLDINGS, L.L.C. | 2002-07-11 | — | — | US | disclosed |