Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7577807 | 0.83 | ACHE (0.43) | GPR3HTR2AACHEBCHECHRM2 | |
| SCHEMBL6673985 | 0.82 | GPR3 (0.41) | GPR3HTR2AACHEBCHECHRM2 | |
| SCHEMBL7580105 | 0.82 | ACHE (0.33) | GPR3HTR2AACHEBCHECHRM2 | |
| SCHEMBL7197597 | 0.79 | ACHE (0.49) | GPR3HTR2AACHEBCHECHRM2 | |
| SCHEMBL30390148 | 0.73 | GPR3 (0.46) | GPR3HTR2AACHEBCHECHRM2 | |
| SCHEMBL5981387 | 0.73 | GPR3 (0.46) | GPR3HTR2AACHEBCHECHRM2 | |
| SCHEMBL6671925 | 0.73 | GPR3 (0.46) | GPR3HTR2AACHEBCHECHRM2 | |
| SCHEMBL5175634 | 0.73 | GPR3 (0.46) | GPR3HTR2AACHEBCHECHRM2 | |
| SCHEMBL8086443 | 0.73 | GPR3 (0.41) | GPR3HTR2AACHEBCHECHRM2 | |
| SCHEMBL3479971 | 0.72 | ACHE (0.38) | GPR3HTR2AACHEBCHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729968-B1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2002-09-25 | — | — | EP | claimed |
| US-6365764-B1 | METALLOCENE COMPOUNDS HAVING TWO FLUORENYL LIGANDS BRIDGED WITH A SINGLE SILICON OR GERMANIUM ATOM | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-04-02 | — | — | US | claimed |
| EP-0729968-A1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | Montell Technology Company bv (NL) | 1996-09-04 | — | — | EP | claimed |
| EP-0729968-B1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2002-09-25 | — | — | EP | disclosed |
| US-6180733-B1 | OLEFIN POLYMERIZATION USING CATALYST COMPRISING THE PRODUCT OF REACTION BETWEEN A GROUP 4 OR 5 METALLOCENE COMPOUND AND AN ALUMOXANE, OPTIONALLY WITH ORGANOALUMINUM OR COMPOUND ABLE TO GIVE A METALLOCENE ALKYL CATION; ATACTIC POLYPROPYLENE | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-01-30 | — | — | US | disclosed |
| EP-0729968-A1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | Montell Technology Company bv (NL) | 1996-09-04 | — | — | EP | disclosed |