Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573146 | 0.90 | GRIN2D (0.44) | MEN1CYP1A2CYP2C9KMT2AMAOB | |
| SCHEMBL7573148 | 0.90 | GRIN2D (0.44) | MEN1CYP1A2CYP2C9KMT2AMAOB | |
| SCHEMBL7573475 | 0.86 | NFE2L2 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7571219 | 0.86 | ACHE (0.47) | MEN1CYP1A2CYP2C9KMT2AMAOA | |
| SCHEMBL7572694 | 0.84 | MAPT (0.45) | CYP1A2CYP2C9MAOAMAOBMAPT | |
| SCHEMBL7572697 | 0.84 | MAPT (0.45) | CYP1A2CYP2C9MAOAMAOBMAPT | |
| SCHEMBL7579065 | 0.83 | MEN1 (0.49) | MEN1CYP1A2CYP3A4CYP2C9KMT2A | |
| SCHEMBL7579070 | 0.83 | MEN1 (0.49) | MEN1CYP1A2CYP3A4CYP2C9KMT2A | |
| SCHEMBL7581527 | 0.83 | MEN1 (0.49) | MEN1CYP1A2CYP3A4CYP2C9KMT2A | |
| SCHEMBL7581536 | 0.83 | MEN1 (0.49) | MEN1CYP1A2CYP3A4CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |