SCHEMBL7581287

SCHEMBL7581287

CCNC(=O)C(C)OC(=O)Nc1ccccc1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.43
LMNA P02545 3/20 0.43
KDM4E B2RXH2 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
THRB P10828 1/20 0.42
MEN1 O00255 1/20 0.41
TTR P02766 1/20 0.41
PPOX P50336 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
EGFR P00533 1/20 0.40
ERBB2 P04626 1/20 0.40
MRGPRX4 Q96LA9 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
CRHR1 P34998 1/20 0.36
STK39 Q9UEW8 1/20 0.36
BRAF P15056 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactofen SCHEMBL7587716 0.85 TDP1 (0.52) FFAR1LMNAKDM4EGAAMAPT
Acifluorfen SCHEMBL7580482 0.84 MEN1 (0.64) FFAR1LMNAMAPTMEN1TTR
Desmedipham SCHEMBL7587219 0.84 FFAR1 (0.41) FFAR1LMNAMAPTHPGDMEN1
SCHEMBL4889531 0.83 FFAR1 (0.56) FFAR1LMNAKDM4EGAAMAPT
SCHEMBL15844933 0.83 FFAR1 (0.56) FFAR1LMNAKDM4EGAAMAPT
SCHEMBL39100 0.83 FFAR1 (0.56) FFAR1LMNAKDM4EGAAMAPT
SCHEMBL2681468 0.83 FFAR1 (0.56) FFAR1LMNAKDM4EGAAMAPT
SCHEMBL7589396 0.81 MEN1 (0.51) FFAR1LMNAMAPTTHRBMEN1
Oxyfluorfen SCHEMBL7584610 0.81 MEN1 (0.50) FFAR1LMNAMAPTMEN1TTR
Propanil SCHEMBL7590514 0.80 FFAR1 (0.46) FFAR1LMNAKDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT FFAR1 4198/4885LMNA 3881/4885KDM4E 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.