Desmedipham

Desmedipham

SCHEMBL7587219

CCOC(=O)Nc1cccc(OC(=O)Nc2ccccc2)c1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.41
LMNA P02545 2/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
STK39 Q9UEW8 1/20 0.40
EGFR P00533 2/20 0.39
ERBB2 P04626 2/20 0.39
MEN1 O00255 1/20 0.39
TTR P02766 1/20 0.39
PPOX P50336 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MTNR1B P49286 1/20 0.39
MRGPRX4 Q96LA9 2/20 0.39
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
CRHBP P24387 1/20 0.38
RAB9A P51151 1/20 0.38
CRHR2 Q13324 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenmedipham SCHEMBL7585413 0.89 FAAH (0.48) FFAR1LMNAMAPTMAPK1STK39
SCHEMBL7581287 0.84 FFAR1 (0.43) FFAR1LMNAMAPTSTK39EGFR
Acifluorfen SCHEMBL7582925 0.82 TDP1 (0.64) LMNAMAPTSTK39EGFRERBB2
SCHEMBL4889531 0.81 FFAR1 (0.56) FFAR1LMNAMAPTMEN1TTR
SCHEMBL2681468 0.81 FFAR1 (0.56) FFAR1LMNAMAPTMEN1TTR
SCHEMBL15844933 0.81 FFAR1 (0.56) FFAR1LMNAMAPTMEN1TTR
SCHEMBL39100 0.81 FFAR1 (0.56) FFAR1LMNAMAPTMEN1TTR
Desmedipham SCHEMBL7577677 0.81 MEN1 (0.53) LMNAMAPTSTK39EGFRERBB2
Fluometuron SCHEMBL7584025 0.81 TP53 (0.50) FFAR1LMNAMAPTSTK39MEN1
Propanil SCHEMBL7590514 0.80 FFAR1 (0.46) FFAR1LMNAMAPTSTK39EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT FFAR1 4198/4885LMNA 3881/4885MAPT 1092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.