Isoxaflutole

Isoxaflutole

SCHEMBL7581791

CS(=O)(=O)c1cc(C(F)(F)F)ccc1C(=O)c1cnoc1C1CC1.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
VDR P11473 1/20 0.36
NPY5R Q15761 2/20 0.34
DHODH Q02127 1/20 0.33
FLT1 P17948 1/20 0.33
FLT4 P35916 1/20 0.33
KDR P35968 1/20 0.33
NR1I2 O75469 1/20 0.33
CACNA1B Q00975 1/20 0.33
MAPT P10636 2/20 0.32
GABRP O00591 2/20 0.32
GABRD O14764 2/20 0.32
GABRA1 P14867 2/20 0.32
GABRB1 P18505 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRA3 P34903 2/20 0.32
GABRA2 P47869 2/20 0.32
GABRB2 P47870 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7584743 0.95 FLT1 (0.33) THRBVDRNPY5RDHODHFLT1
Isoxaflutole SCHEMBL7581314 0.90 THRB (0.33) THRBVDRNPY5RFLT1FLT4
Isoxaflutole SCHEMBL7583680 0.89 GRM4 (0.32) THRBVDR
Isoxaflutole SCHEMBL7586601 0.88 THRB (0.33) THRBVDRNPY5R
Glyphosate SCHEMBL7585490 0.86 NPY5R (0.31) THRBVDRNPY5RFLT1FLT4
Glufosinate SCHEMBL7578596 0.85 GRM8 (0.32)
Glyphosate SCHEMBL7580586 0.84 THRB (0.30) THRBVDR
Isoxaflutole SCHEMBL7584184 0.83 MEN1 (0.31) MAPTMEN1KMT2AALDH1A1
Isoxaflutole SCHEMBL21645075 0.80 DHODH (0.48) THRBNPY5RDHODHNR1I2CACNA1B
Isoxaflutole SCHEMBL66989 0.80 DHODH (0.48) THRBNPY5RDHODHNR1I2CACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT THRB 2326/4885VDR 4411/4885NPY5R 2015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.