Glyphosate

Glyphosate

SCHEMBL7585490

CS(=O)(=O)c1cc(Cl)ccc1C(=O)c1cnoc1C1CC1.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl.O=C(O)CNCP(=O)(O)O

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 1/20 0.31
FLT1 P17948 1/20 0.30
FLT4 P35916 1/20 0.30
KDR P35968 1/20 0.30
THRB P10828 1/20 0.30
VDR P11473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoxaflutole SCHEMBL7581314 0.96 THRB (0.33) NPY5RFLT1FLT4KDRTHRB
Glyphosate SCHEMBL7580586 0.94 THRB (0.30) THRBVDR
Isoxaflutole SCHEMBL7586601 0.90 THRB (0.33) NPY5RTHRBVDR
SCHEMBL7584743 0.90 FLT1 (0.33) NPY5RFLT1FLT4KDRTHRB
Glufosinate SCHEMBL7578596 0.86 GRM8 (0.32)
Isoxaflutole SCHEMBL7581791 0.86 THRB (0.36) NPY5RFLT1FLT4KDRTHRB
Isoxaflutole SCHEMBL7587167 0.82
Isoxaflutole SCHEMBL7583680 0.82 GRM4 (0.32) THRBVDR
Acifluorfen SCHEMBL7575603 0.82 TDP1 (0.49) FLT1FLT4KDRTHRBVDR
Glyphosate SCHEMBL7575525 0.81 GABRA2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT NPY5R 2015/4885FLT1 4191/4885FLT4 4355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.