Sugi Predict

Sugi Predict / Compounds / SCHEMBL7582136

SCHEMBL7582136

SCHEMBL7582136

CCC(F)c1cc(N2CCN(CO)CC2)cc(Br)c1Cl

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ DRD2 P14416 2/20 0.33
▸ DRD3 P35462 2/20 0.33
▸ CCR1 P32246 1/20 0.32
▸ IGF1R P08069 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7582764 0.90 DRD2 (0.38) DRD2DRD3
SCHEMBL7586573 0.88 KDM4E (0.36) DRD2DRD3
SCHEMBL7582141 0.87 KDM4E (0.38) DRD2DRD3
SCHEMBL7581935 0.86 KDM4E (0.40) DRD2
SCHEMBL7581291 0.86 KDM4E (0.40) DRD2
SCHEMBL7585537 0.83 DRD4 (0.48) DRD2DRD3
SCHEMBL7590671 0.82 CHRNB2 (0.45) DRD2DRD3
SCHEMBL7584867 0.82 CHRNB2 (0.45) DRD2DRD3
SCHEMBL7581302 0.81 SLC6A2 (0.33) CCR1
SCHEMBL7585007 0.80 MAPT (0.51) CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675118-B1 Biphenylderivatives, process for their preparation and their use as medicaments EISAI CO LTD (JP) 2002-10-09 — — EP disclosed
US-6281214-B1 USEFUL FOR TREATING AND AMELIORATING MENTAL DISORDERS EISAI CO., LTD (JP) 2001-08-28 — — US disclosed
EP-0675118-A2 Biphenylderivatives, process for their preparation and their use as medicaments Eisai Co., Ltd. (JP) 1995-10-04 — — EP disclosed