SCHEMBL7582199

SCHEMBL7582199

CCc1cccc(OB(O)O)c1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
KDM4E B2RXH2 4/20 0.44
ALDH1A1 P00352 4/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
SOD1 P00441 1/20 0.43
POLB P06746 2/20 0.40
GAA P10253 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29172589 0.85 ALOX5 (0.45)
SCHEMBL28626028 0.84 KDM4E (0.46) MAPK1L3MBTL1TSHRTDP1KDM4E
SCHEMBL26743095 0.84 SMN1; SMN2 (0.44) MAPK1L3MBTL1TSHRTDP1KDM4E
SCHEMBL1250219 0.82 ENPP2 (0.52) TSHRSMN1; SMN2
SCHEMBL6398311 0.82 LPL (0.53)
SCHEMBL29172596 0.81 LPL (0.59)
SCHEMBL31013531 0.81 LPL (0.59)
SCHEMBL29643534 0.81 ENPP2 (0.48) ALDH1A1SMN1; SMN2
SCHEMBL27569009 0.81 ENPP2 (0.48) ALDH1A1SMN1; SMN2
SCHEMBL4184944 0.81 TSHR (0.38) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115928264-B Preparation method of continuous silicon carbide fiber containing metal in near-stoichiometric ratio 湖南泽睿新材料有限公司 2024-02-20 CN claimed
CN-115928264-B Preparation method of continuous silicon carbide fiber containing metal in near-stoichiometric ratio 湖南泽睿新材料有限公司 2024-02-20 CN disclosed
CN-117362670-A Metal organic framework material based on octatetrathiophene, preparation method and application thereof in heavy metal adsorption 南京理工大学 2024-01-09 CN disclosed
CN-105263930-B As the aryl-pyrrolidine and pyridine derived compound of LRRK2 inhibitor H.隆德贝克有限公司 2017-06-09 CN disclosed
EP-0675118-B1 Biphenylderivatives, process for their preparation and their use as medicaments EISAI CO LTD (JP) 2002-10-09 EP disclosed
US-6281214-B1 USEFUL FOR TREATING AND AMELIORATING MENTAL DISORDERS EISAI CO., LTD (JP) 2001-08-28 US disclosed
EP-0675118-A2 Biphenylderivatives, process for their preparation and their use as medicaments Eisai Co., Ltd. (JP) 1995-10-04 EP disclosed