Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AGXT | P21549 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1250219 | 0.82 | ENPP2 (0.52) | TSHRMAOBCYP4F2CYP4A11IDO1 | |
| SCHEMBL7582199 | 0.81 | MAPK1 (0.44) | TSHRALDH1A1 | |
| SCHEMBL29643534 | 0.81 | ENPP2 (0.48) | ALDH1A1MAOBTAAR1 | |
| SCHEMBL27569009 | 0.81 | ENPP2 (0.48) | ALDH1A1MAOBTAAR1 | |
| SCHEMBL29654293 | 0.80 | NOS1 (0.45) | TSHRALDH1A1CETPBCHEHSD17B10 | |
| SCHEMBL28111443 | 0.80 | NOS1 (0.45) | TSHRALDH1A1CETPBCHEHSD17B10 | |
| SCHEMBL27896280 | 0.79 | CYP4F2 (0.57) | ALDH1A1CYP4F2CYP4A11TAAR1 | |
| Hydrochloric Acid SCHEMBL28156681 | 0.79 | ENPP2 (0.47) | ALDH1A1MAOBIDO1AGXTTAAR1 | |
| SCHEMBL6677730 | 0.79 | ENPP2 (0.41) | TSHRALDH1A1 | |
| SCHEMBL29172589 | 0.78 | ALOX5 (0.45) | CYP4F2CYP4A11TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978517-A | Preparation method and application of radioactive probe targeting monoamine oxidase B | 中国科学院高能物理研究所 | 2024-11-19 | — | — | CN | claimed |
| CN-117797651-A | Preparation method and separation application of charge reversible pore-balancing membrane | 浙江工业大学 | 2024-04-02 | — | — | CN | claimed |
| CN-117797651-A | Preparation method and separation application of charge reversible pore-balancing membrane | 浙江工业大学 | 2024-04-02 | — | — | CN | disclosed |
| WO-2023165523-A1 | AROMATIC RING-SUBSTITUTED METHOXY DERIVATIVE AND USE THEREOF | 上海璎黎药业有限公司 | 2023-09-07 | — | — | WO | disclosed |
| CN-116693514-A | Aromatic ring substituted methoxy derivative and application thereof | 上海璎黎药业有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116284080-A | Dihydropyrimidine derivative containing boric acid and boric acid pinacol ester group, and preparation method and application thereof | 山东大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-112920208-B | Boric acid-containing indole aryl sulfone derivative and preparation method and application thereof | 山东大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-108700686-A | Colored resin composition for color filter, pigment dispersion liquid, color filter, and display device | DNP精细化工股份有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-107003448-A | Color material dispersion liquid, photosensitive colored resin composition, color filter, liquid crystal display device, and organic light-emitting display device | DNP精细化工股份有限公司 | 2017-08-01 | — | — | CN | disclosed |
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRUENENTHAL GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRM1, GRIN1, GRM2 | TSHR 991/4885TRPA1 1375/4885ALDH1A1 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.