Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659512 | 0.78 | CYP1A2 (0.41) | KDM4EGAAMAPTALOX12NOTUM | |
| SCHEMBL3023333 | 0.77 | GABRP (0.45) | NOTUMKMONPC1RAB9ACA12 | |
| SCHEMBL13915420 | 0.74 | AHR (0.45) | AHRCYP1B1HTTMEN1KMT2A | |
| SCHEMBL11079495 | 0.73 | ALOX15 (0.43) | HTTMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL3646655 | 0.73 | GSTP1 (0.52) | CYP1B1MEN1KMT2AKDM4ENOTUM | |
| SCHEMBL1473646 | 0.71 | PTPRC (0.46) | CYP1B1MEN1KMT2AGAAMAPT | |
| SCHEMBL9467973 | 0.71 | HSD17B3 (0.50) | HTTMAPTPGR | |
| SCHEMBL1471565 | 0.71 | MAPT (0.46) | KMT2AKDM4EMAPTNOTUMKMO | |
| SCHEMBL29242287 | 0.71 | KMO (0.42) | HTTMEN1KMT2AMAPTPKM | |
| SCHEMBL210321 | 0.70 | BACE1 (0.50) | HTTMEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476061-B1 | Fungicides containing pyrrolidones as their active agents | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-05 | — | — | US | disclosed |
| EP-1133229-B1 | FUNGICIDES CONTAINING PYRROLIDONES AS THEIR ACTIVE AGENTS | BASF AG (DE) | 2002-10-09 | — | — | EP | disclosed |
| EP-1133229-A1 | FUNGICIDES CONTAINING PYRROLIDONES AS THEIR ACTIVE AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000030445-A1 | FUNGICIDES CONTAINING PYRROLIDONES AS THEIR ACTIVE AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-02 | — | — | WO | disclosed |
| US-5206392-A | Reacting arylacetonitriles with glyoxylic acid in presence of base, hydrolyzing, cyclizing | AMERICAN CYANAMID COMPANY (US) | 1993-04-27 | — | — | US | disclosed |