Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | BAX | Q07812 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | TLR4 | O00206 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 3/20 | 0.46 |
| ▸ | CRHBP | P24387 | 3/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4847049 | 0.93 | GPR35 (0.58) | GPR35KDM4EMEN1KMT2ATHRB | |
| SCHEMBL4840927 | 0.92 | GPR35 (0.53) | GPR35KDM4ETHRBTDP1ALDH1A1 | |
| SCHEMBL4843320 | 0.87 | GPR35 (0.51) | GPR35KDM4EMEN1KMT2ATTR | |
| SCHEMBL1602832 | 0.87 | MAPK1 (0.51) | GPR35KDM4ELTA4HNR1H2BAX | |
| SCHEMBL4839671 | 0.86 | GPR35 (0.55) | GPR35KDM4EMEN1KMT2ATHRB | |
| SCHEMBL5955410 | 0.85 | LTA4H (0.52) | GPR35LTA4HMEN1KMT2ATDP1 | |
| SCHEMBL10717379 | 0.84 | ALDH1A1 (0.55) | KDM4ELTA4HMEN1KMT2ATTR | |
| SCHEMBL4841623 | 0.84 | PTPN1 (0.50) | GPR35KDM4ETDP1ALDH1A1SOS1 | |
| SCHEMBL6186809 | 0.84 | GPR35 (0.49) | GPR35KDM4EMEN1KMT2ATHRB | |
| SCHEMBL4845296 | 0.84 | GPR35 (0.49) | GPR35KDM4EMEN1KMT2ATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011802-B1 | PHENOXY-PHENOXY-PROPIONIC ACID AMIDES, PROCESSES FOR THEIR PREPARATION, HERBICIDAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN CONTROLLING THE GROWTH OF WEEDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-09-15 | — | — | EP | claimed |
| US-20260022122-A1 | NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME | CHECKMATE THERAPEUTICS INC. (KR) | 2026-01-22 | — | — | US | disclosed |
| EP-4562015-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026481-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| US-11883387-B2 | PqsR inverse agonists | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2024-01-30 | — | — | US | disclosed |
| WO-2023229346-A1 | NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME | 주식회사 체크메이트테라퓨틱스 | 2023-11-30 | — | — | WO | disclosed |
| US-20210353606-A1 | PqsR INVERSE AGONISTS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2021-11-18 | — | — | US | disclosed |
| EP-3818045-A1 | PQSR INVERSE AGONISTS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2021-05-12 | — | — | EP | disclosed |
| WO-2020007938-A1 | PqsR INVERSE AGONISTS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2020-01-09 | — | — | WO | disclosed |
| EP-1013635-B1 | Preparation of diphenylethers | DOW AGROSCIENCES LLC (US) | 2002-09-18 | — | — | EP | disclosed |
| EP-1013635-A1 | Preparation of diphenylethers | ROHM AND HAAS COMPANY (US) | 2000-06-28 | — | — | EP | disclosed |
| EP-1013635-A1 | Preparation of diphenylethers | ROHM AND HAAS COMPANY (US) | 2000-06-28 | — | — | EP | disclosed |
| EP-0011802-B1 | PHENOXY-PHENOXY-PROPIONIC ACID AMIDES, PROCESSES FOR THEIR PREPARATION, HERBICIDAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN CONTROLLING THE GROWTH OF WEEDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-09-15 | — | — | EP | disclosed |
| EP-0011802-A1 | Phenoxy-phenoxy-propionic acid amides, processes for their preparation, herbicidal compositions containing them and their use in controlling the growth of weeds | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-06-11 | — | — | EP | disclosed |
| EP-0011802-A1 | Phenoxy-phenoxy-propionic acid amides, processes for their preparation, herbicidal compositions containing them and their use in controlling the growth of weeds | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11883387-B2 | PqsR inverse agonists | QRFPR, P2RY11, QARS1 | GPR35 11/4885KDM4E 3629/4885LTA4H 1192/4885 |
| US-20210353606-A1 | PqsR INVERSE AGONISTS | QRFPR, P2RY11, QARS1 | GPR35 11/4885KDM4E 3629/4885LTA4H 1192/4885 |
| US-20260022122-A1 | NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME | NAMPT, NAPRT, NNT | GPR35 2281/4885KDM4E 2601/4885LTA4H 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.