Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573660 | 0.88 | NPC1 (0.46) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL7240252 | 0.79 | NPC1 (0.51) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL7574535 | 0.79 | F10 (0.45) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL8436505 | 0.75 | KMT2A (0.44) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL6228359 | 0.75 | NPC1 (0.49) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL7585606 | 0.74 | ALDH1A1 (0.39) | KMT2ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7578629 | 0.73 | RAB9A (0.54) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL6127974 | 0.73 | JAK2 (0.69) | NPC1RAB9AMAPTSMN1; SMN2MAOB | |
| SCHEMBL8436507 | 0.70 | NPC1 (0.41) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL17845891 | 0.70 | KMT2A (0.49) | KMT2AMEN1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882730-B1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-0882730-A1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-12-09 | — | — | EP | disclosed |