Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | PNLIP | P16233 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573660 | 0.84 | NPC1 (0.46) | NPC1RAB9ALMNAHTTKMT2A | |
| SCHEMBL7583446 | 0.79 | KMT2A (0.50) | NPC1RAB9ALMNAHTTKMT2A | |
| SCHEMBL8436507 | 0.75 | NPC1 (0.41) | F10NPC1RAB9ALMNAHTT | |
| SCHEMBL7574870 | 0.74 | ALDH1A1 (0.39) | NPC1RAB9AHTTKMT2ASMN1; SMN2 | |
| SCHEMBL7583871 | 0.73 | NPC1 (0.51) | NPC1RAB9ALMNAHTTKMT2A | |
| SCHEMBL7240252 | 0.71 | NPC1 (0.51) | F10NPC1RAB9ALMNAHTT | |
| SCHEMBL10387050 | 0.70 | NPC1 (0.54) | NPC1RAB9ALMNAHTTKMT2A | |
| SCHEMBL1180898 | 0.69 | PRNP (0.34) | NPC1RAB9ALMNAHTTKMT2A | |
| SCHEMBL7573916 | 0.69 | MAPK1 (0.53) | NPC1RAB9ALMNAHTTKMT2A | |
| SCHEMBL10388317 | 0.68 | THRB (0.31) | NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882730-B1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-0882730-A1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-12-09 | — | — | EP | disclosed |