Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583446 | 0.88 | KMT2A (0.50) | NPC1RAB9ALMNAHTTSMO | |
| SCHEMBL7574535 | 0.84 | F10 (0.45) | NPC1RAB9ALMNAHTTMAPK1 | |
| SCHEMBL7585606 | 0.76 | ALDH1A1 (0.39) | NPC1RAB9ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL7583871 | 0.75 | NPC1 (0.51) | NPC1RAB9ALMNAHTTMAPK1 | |
| SCHEMBL2117583 | 0.73 | SMO (0.75) | NPC1RAB9ALMNAMAPK1SMO | |
| SCHEMBL1181086 | 0.71 | ALDH1A1 (0.45) | MAPK1SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL7573916 | 0.71 | MAPK1 (0.53) | NPC1RAB9ALMNAHTTMAPK1 | |
| SCHEMBL1968479 | 0.69 | NR4A2 (0.41) | NPC1RAB9ALMNAHTTMAPK1 | |
| SCHEMBL7574566 | 0.69 | MAPK1 (0.64) | NPC1RAB9ALMNAMAPK1SMN1; SMN2 | |
| SCHEMBL10939703 | 0.69 | NPC1 (0.76) | NPC1RAB9ALMNAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882730-B1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-5985858-A | TREATING AND PREVENTING HYPERLIPIDEMIA, DIABETES AND CATARACT, OR AS AN ANTITUMOR AGENT | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0882730-A1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-12-09 | — | — | EP | disclosed |