Pentoxazone

Pentoxazone

SCHEMBL7583665

CC(C)=C1OC(=O)N(c2cc(OC3CCCC3)c(Cl)cc2F)C1=O.CC(Oc1ccc(Oc2nc3ccc(Cl)cc3o2)cc1)C(=O)O

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPOX P50336 3/20 0.34
PPARG P37231 4/20 0.31
PTGDR2 Q9Y5Y4 2/20 0.31
PTGDR Q13258 1/20 0.31
P2RX3 P56373 2/20 0.30
GPR6 P46095 1/20 0.30
CTSL P07711 1/20 0.30
CTSS P25774 1/20 0.30
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentoxazone SCHEMBL7587243 0.87 TP53 (0.42) PPOXPTGDR2PTGDRP2RX3GPR6
Pentoxazone SCHEMBL7583345 0.84 PPOX (0.37) PPOXPTGS1PTGS2
Pentoxazone SCHEMBL7580654 0.82 TSHR (0.45) PPOXPTGDR2PTGDR
Pentoxazone SCHEMBL7588179 0.82 PPOX (0.41) PPOXPTGDRP2RX3
Pentoxazone SCHEMBL7582107 0.81 SLC6A9 (0.36) PPOXGPR6
Pentoxazone SCHEMBL7577616 0.81 LIPE (0.36) PPOX
Propaquizafop SCHEMBL7580397 0.79 TP53 (0.39) PPOX
Flumipropyn SCHEMBL7578730 0.77 PPOX (0.35) PPOXPPARGP2RX3
Pentoxazone SCHEMBL29355372 0.77 PPOX (0.51) PPOX
Pentoxazone SCHEMBL38904 0.77 PPOX (0.51) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT PPOX 1/4885PPARG 777/4885PTGDR2 3560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.