Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.44 |
| ▸ | SMO | Q99835 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20060617 | 0.78 | SMO (0.45) | SMO | |
| SCHEMBL5847190 | 0.76 | L3MBTL1 (0.48) | HSD11B1KMT2AMEN1CRHR1SMO | |
| SCHEMBL18356854 | 0.76 | CNR2 (0.44) | KMT2AMEN1CRHR1SMOMAPT | |
| SCHEMBL4438627 | 0.74 | SMO (0.53) | SMO | |
| SCHEMBL7041005 | 0.71 | HSD11B1 (0.45) | HSD11B1CRHR1HPGDMAPTHSP90AB1 | |
| SCHEMBL6101031 | 0.71 | CRHR1 (0.48) | HSD11B1CRHR1HPGDHSP90AB1HSP90AA1 | |
| SCHEMBL7573568 | 0.71 | CNR2 (0.43) | KMT2ASMO | |
| SCHEMBL16572947 | 0.71 | KMT2A (0.53) | KMT2AMEN1SMOHPGDMAPT | |
| SCHEMBL8746755 | 0.70 | MAPT (0.49) | HSD11B1KMT2ACRHR1HPGDMAPT | |
| SCHEMBL7583757 | 0.69 | HSD11B1 (0.50) | HSD11B1KMT2AMEN1CRHR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773248-B1 | Polymers with heterocyclic side groups | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-5668245-A | PHENYLENE POLYMERS WITH HETEROCYCLIC SIDE GROUPS | MAXDEM INCORPORATED (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0773248-A1 | Polymers with heterocyclic side groups | MAXDEM INCORPORATED (US) | 1997-05-14 | — | — | EP | disclosed |