Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 10/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28694001 | 0.87 | IDO1 (0.51) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL2186978 | 0.78 | TUBB4A (0.51) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL28691199 | 0.73 | GPR84 (0.50) | GPR84HTR2AHTR1A | |
| SCHEMBL20584073 | 0.73 | GPR84 (0.62) | GPR84MPOTSHRHTR2ATRPM8 | |
| SCHEMBL28534743 | 0.72 | IDO1 (0.54) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL5307324 | 0.70 | IDO1 (0.62) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL5326763 | 0.70 | MPO (0.59) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL208748 | 0.70 | GPR84 (0.58) | GPR84MPOTSHRHTR2ATRPM8 | |
| SCHEMBL28534770 | 0.69 | IDO1 (0.49) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL22802302 | 0.69 | TUBB4A (0.58) | IDO1GPR84TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002205983-A | INDOLE DERIVATIVE | NIPPON KAYAKU CO LTD | 2002-07-23 | — | — | JP | disclosed |