SCHEMBL7584497

SCHEMBL7584497

Cc1c(C)c(O)c(C2CCc3ccccc32)c(O)c1C

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.42
PIN1 Q13526 3/20 0.42
ADRA1A P35348 1/20 0.42
SIGMAR1 Q99720 1/20 0.41
CETP P11597 1/20 0.39
IDO1 P14902 2/20 0.39
CYP11B2 P19099 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
TAS1R2 Q8TE23 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7584485 0.90 PIN1 (0.40) PDPK1PIN1ADRA1ASIGMAR1CETP
SCHEMBL6447446 0.78 IDO1 (0.40) PDPK1ADRA1ASIGMAR1IDO1CYP11B2
SCHEMBL9317554 0.75 PIN1 (0.44) PDPK1PIN1ADRA1ASIGMAR1CETP
SCHEMBL4277910 0.73 ADRA1A (0.39) PDPK1PIN1ADRA1ASIGMAR1IDO1
SCHEMBL5710152 0.73 PIN1 (0.51) PDPK1PIN1ADRA1ASIGMAR1IDO1
SCHEMBL8849605 0.73 DDB1 (0.53) PDPK1ADRA1ASIGMAR1IDO1CYP11B2
SCHEMBL652932 0.73 ADRA1A (0.37) PDPK1PIN1ADRA1ASIGMAR1IDO1
SCHEMBL6597324 0.73 ADRA1A (0.37) PDPK1PIN1ADRA1ASIGMAR1IDO1
SCHEMBL15846513 0.72 PIN1 (0.47) PDPK1PIN1ADRA1ASIGMAR1CETP
SCHEMBL8735629 0.72 ADRA1A (0.46) PDPK1PIN1ADRA1ASIGMAR1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0994836-B1 METHOD FOR PRODUCING AND PURIFYING 3-(4-HYDROXYPHENYL)-1,1,3-TRIMETHYLINDAN-5-OL BAYER AG (DE) 2002-10-02 EP disclosed