Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133896 | 0.78 | HTR2A (0.49) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 | |
| SCHEMBL652932 | 0.78 | ADRA1A (0.37) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 | |
| SCHEMBL6597324 | 0.78 | ADRA1A (0.37) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 | |
| SCHEMBL28886942 | 0.77 | ADRA1A (0.43) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 | |
| SCHEMBL29390302 | 0.74 | SIGMAR1 (0.62) | ADRA1ASIGMAR1CYP11B2TAAR1CYP2D6 | |
| SCHEMBL503849 | 0.74 | SIGMAR1 (0.62) | ADRA1ASIGMAR1CYP11B2TAAR1CYP2D6 | |
| SCHEMBL28806293 | 0.72 | ADRA1A (0.49) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 | |
| Ammonia Solution, Strong SCHEMBL8210515 | 0.72 | SIGMAR1 (0.60) | ADRA1ASIGMAR1CYP11B2TAAR1CYP2D6 | |
| SCHEMBL14247675 | 0.72 | ADRA1A (0.49) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 | |
| SCHEMBL30606845 | 0.72 | SIGMAR1 (0.60) | ADRA1ASIGMAR1CYP11B2TAAR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863118-A1 | Preparation of Brominated Indanes | ALBEMARLE CORPORATION (US) | 1998-09-09 | — | — | EP | claimed |