SCHEMBL9317554

SCHEMBL9317554

Oc1cc(O)c(C2CCc3ccccc32)c(O)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 2/20 0.44
ADRA1A P35348 1/20 0.41
DRD1 P21728 3/20 0.39
CETP P11597 1/20 0.38
MAPK1 P28482 3/20 0.38
TP53 P04637 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2D6 P10635 2/20 0.38
HSD17B10 Q99714 2/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
CYP2C19 P33261 1/20 0.38
IDO1 P14902 1/20 0.38
PDPK1 O15530 1/20 0.38
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14283849 0.78 DRD1 (0.47) PIN1ADRA1ADRD1MAPK1TP53
SCHEMBL9316636 0.77 CETP (0.43) PIN1ADRA1ADRD1CETPIDO1
SCHEMBL7584485 0.76 PIN1 (0.40) PIN1ADRA1ACETPIDO1PDPK1
SCHEMBL5710152 0.75 PIN1 (0.51) PIN1ADRA1ADRD1IDO1PDPK1
SCHEMBL7584497 0.75 PDPK1 (0.42) PIN1ADRA1ACETPIDO1PDPK1
SCHEMBL15846513 0.75 PIN1 (0.47) PIN1ADRA1ACETPIDO1PDPK1
SCHEMBL9317569 0.73 CETP (0.47) PIN1CETPALDH1A1
SCHEMBL28306252 0.72 ALOX15 (0.46) PIN1ADRA1ADRD1MAPK1TP53
SCHEMBL8735629 0.70 ADRA1A (0.46) PIN1ADRA1ACYP2D6IDO1PDPK1
SCHEMBL4284576 0.70 PIN1 (0.40) PIN1ADRA1ADRD1MAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0625209-A1 METHOD FOR ASSAYING THE SOD ACTIVITY BY USING A SELF-OXIDIZABLE COMPOUND NECESSARY FOR ITS IMPLEMENTATION, SELF-OXIDIZABLE COMPOUNDS AND PREPARATION THEREOF. BIOXYTECH (FR) 1994-11-23 EP disclosed