Isoproturon

Isoproturon

SCHEMBL7584768

CC(C)c1ccc(NC(=O)N(C)C)cc1.CCOC(=O)/C(Cl)=C/c1cc(N2C(=O)C3=C(CCCC3)C2=O)ccc1Cl

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY12 Q9H244 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
TP53 P04637 2/20 0.34
MAPT P10636 1/20 0.34
PANK3 Q9H999 1/20 0.34
LMNA P02545 3/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
USP2 O75604 1/20 0.33
HTT P42858 1/20 0.33
APEX1 P27695 1/20 0.33
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NPC1 O15118 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dcmu SCHEMBL7576800 0.91 APEX1 (0.43) P2RY12SMN1; SMN2MAPTLMNAALDH1A1
Chlorotoluron SCHEMBL1191511 0.90 APEX1 (0.38) SMN1; SMN2TP53MAPTLMNAALDH1A1
SCHEMBL5467830 0.85 MAPT (0.37) MAPTALDH1A1HPGDHTTKMT2A
SCHEMBL39177 0.85 MAPT (0.37) MAPTALDH1A1HPGDHTTKMT2A
Fluometuron SCHEMBL7590551 0.84 TP53 (0.44) SMN1; SMN2TP53MAPTALDH1A1HPGD
Propanil SCHEMBL7587656 0.82 CYP3A4 (0.45) P2RY12ALDH1A1HPGDNPSR1KMT2A
Dimefuron SCHEMBL7575030 0.81 MEN1 (0.58) APEX1KMT2A
SCHEMBL8897908 0.79 ALDH1A1 (0.34) MAPTLMNAALDH1A1HPGDNPSR1
SCHEMBL8897906 0.79 ALDH1A1 (0.34) MAPTLMNAALDH1A1HPGDNPSR1
SCHEMBL7580161 0.79 CASP3 (0.32) P2RY12MAPTHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT P2RY12 4519/4885SMN1; SMN2 4618/4885TP53 4303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.