SCHEMBL7585127

SCHEMBL7585127

Cc1cc[nH]c1-c1cccnc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 11/20 0.52
CYP3A4 P08684 5/20 0.52
ALDH1A1 P00352 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP11B1 P15538 1/20 0.51
CYP11B2 P19099 1/20 0.51
NUDT1 P36639 1/20 0.47
CYP2E1 P05181 3/20 0.47
CYP2D6 P10635 3/20 0.47
CYP2C9 P11712 3/20 0.47
CYP2B6 P20813 3/20 0.47
CYP2C19 P33261 3/20 0.47
ALK Q9UM73 1/20 0.46
PIM1 P11309 1/20 0.45
PIM3 Q86V86 1/20 0.45
PIM2 Q9P1W9 1/20 0.45
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28607969 0.77 CYP2A6 (0.52) CYP2A6CYP3A4ALDH1A1CYP1A2CYP11B1
SCHEMBL28140602 0.76 NUDT1 (0.54) CYP2A6CYP3A4ALDH1A1CYP1A2NUDT1
SCHEMBL4457439 0.74 KDM4E (0.42) CYP2A6CYP3A4ALDH1A1CYP2B6KDM4E
SCHEMBL31666453 0.74 HPGDS (0.46) MAPK1NISCH
SCHEMBL27674566 0.74 CYP11B1 (0.49) CYP2A6CYP3A4ALDH1A1CYP1A2CYP11B1
SCHEMBL9270880 0.73 CYP11B2 (0.54) CYP2A6CYP3A4ALDH1A1CYP1A2CYP11B1
SCHEMBL30473120 0.71 CYP2A6 (1.00) CYP2A6CYP3A4ALDH1A1CYP1A2CYP11B1
SCHEMBL29419014 0.71 CYP2A6 (1.00) CYP2A6CYP3A4ALDH1A1CYP1A2CYP11B1
SCHEMBL120088 0.71 CYP2A6 (1.00) CYP2A6CYP3A4ALDH1A1CYP1A2CYP11B1
SCHEMBL14823134 0.71 CYP11B1 (0.53) CYP2A6CYP3A4CYP11B1CYP11B2NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4199915-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING VIRAL INFECTIONS MANENT TOMAS, Lluís (ES) 2023-06-28 EP disclosed
WO-2022038473-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING VIRAL INFECTIONS MANENT TOMAS LLUIS (ES) 2022-02-24 WO disclosed
WO-2002098853-A2 INHIBITORS OF CELL PROLIFERATION, ANGIOGENESIS, FERTILITY, AND MUSCLE CONTRACTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2002-12-12 WO disclosed