Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.45 |
| ▸ | DRD2 | P14416 | 13/20 | 0.45 |
| ▸ | HTR7 | P34969 | 7/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591765 | 0.92 | NPC1 (0.48) | HTR1ADRD2HTR7MEN1MAPK1 | |
| SCHEMBL7591802 | 0.92 | HTR1A (0.46) | HTR1ADRD2HTR7HTR6MEN1 | |
| SCHEMBL7591807 | 0.91 | HTR1A (0.49) | HTR1ADRD2HTR7HTR6MEN1 | |
| SCHEMBL7160985 | 0.83 | ESRRG (0.52) | HTR1ADRD2HTR7HSD17B10SIRT6 | |
| SCHEMBL7587006 | 0.82 | NPBWR1 (0.46) | DRD2DRD1MEN1MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL7154175 | 0.81 | ESRRG (0.50) | HTR1ADRD2HTR7MEN1KMT2A | |
| SCHEMBL7583215 | 0.79 | NPC1 (0.41) | HTR1ADRD2HTR7HTR6MEN1 | |
| SCHEMBL7585905 | 0.78 | NPSR1 (0.48) | HTR1ADRD2HTR7DRD1HTR2A | |
| SCHEMBL7582824 | 0.77 | NPC1 (0.45) | HTR1ADRD2HTR7DRD1MEN1 | |
| SCHEMBL7162765 | 0.76 | HTR1A (0.50) | HTR1ADRD2HTR7HTR6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957099-B1 | Heterocyclic carboxamides | PFIZER PROD INC (US) | 2002-11-20 | — | — | EP | claimed |