Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.42 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.42 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591765 | 0.91 | NPC1 (0.48) | NPBWR1MCHR1MEN1KMT2APOLB | |
| SCHEMBL7158123 | 0.85 | AKT3 (0.52) | NPBWR1MCHR1MEN1KMT2APOLB | |
| SCHEMBL7585905 | 0.84 | NPSR1 (0.48) | NPBWR1MCHR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7586281 | 0.82 | HTR1A (0.45) | MEN1KMT2ADRD2DRD1MAPK1 | |
| SCHEMBL7591802 | 0.81 | HTR1A (0.46) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL7591805 | 0.81 | ALDH1A1 (0.47) | NPBWR1MCHR1TAAR1MEN1KMT2A | |
| SCHEMBL7591807 | 0.80 | HTR1A (0.49) | MEN1KMT2AMAPTDRD2USP2 | |
| SCHEMBL7583215 | 0.78 | NPC1 (0.41) | NPBWR1MCHR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7257324 | 0.77 | NPBWR1 (0.49) | NPBWR1MCHR1MEN1KMT2APOLB | |
| SCHEMBL7582824 | 0.76 | NPC1 (0.45) | NPBWR1MCHR1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957099-B1 | Heterocyclic carboxamides | PFIZER PROD INC (US) | 2002-11-20 | — | — | EP | claimed |