Iodosulfuron

Iodosulfuron

SCHEMBL7586575

COc1nc(C)nc(NC(=O)NS(=O)(=O)c2cc(I)ccc2C(=O)O)n1.C[C@H](OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl)C(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
MEN1 O00255 1/20 0.36
TTR P02766 1/20 0.36
PPOX P50336 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
THRB P10828 1/20 0.35
FFAR1 O14842 2/20 0.33
PYGL P06737 1/20 0.32
PYGM P11217 1/20 0.32
MRGPRX4 Q96LA9 1/20 0.30
SCN8A Q9UQD0 1/20 0.30
SCN10A Q9Y5Y9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7582061 0.92 MEN1 (0.37) LMNAMAPTKDM4EGAAHPGD
Iodosulfuron SCHEMBL7584927 0.90 KDM4E (0.31) LMNAMAPTKDM4EGAAHPGD
Chlorsulfuron SCHEMBL7578067 0.90 KDM4E (0.38) LMNAMAPTKDM4EGAAHPGD
SCHEMBL7588445 0.88 LMNA (0.35) LMNAMAPTKDM4EGAAHPGD
Lactofen SCHEMBL7580621 0.87 TDP1 (0.45) LMNAMAPTKDM4EGAAHPGD
Thifensulfuron-Methyl SCHEMBL7582910 0.87 LMNA (0.35) LMNAMAPTKDM4EGAAHPGD
Iodosulfuron SCHEMBL7589756 0.86 TDP1 (0.54) LMNAMAPTMEN1TTRPPOX
Prosulfuron SCHEMBL7575335 0.86 LMNA (0.34) LMNAMAPTKDM4EGAAHPGD
Logran SCHEMBL7576657 0.85 KDM4E (0.34) LMNAMAPTKDM4EGAAHPGD
SCHEMBL7585257 0.83 KDM4E (0.32) LMNAMAPTKDM4EGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT LMNA 3881/4885MAPT 1092/4885KDM4E 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.