Oxyfluorfen

Oxyfluorfen

SCHEMBL7586673

CC1COc2ccccc2N1C(=O)C(Cl)Cl.CCOc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].CCc1cccc(C)c1N(C(=O)CCl)C(C)COC

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
TTR P02766 1/20 0.35
PPOX P50336 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 4/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 2/20 0.31
PPARD Q03181 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL7576510 0.94 MEN1 (0.44) MEN1KMT2ATTRPPOXTDP1
Oxyfluorfen SCHEMBL7581251 0.93 LMNA (0.32) MEN1KMT2ATTRPPOXTDP1
Oxyfluorfen SCHEMBL7588106 0.93 MEN1 (0.31) MEN1KMT2ATTRPPOXTDP1
Oxyfluorfen SCHEMBL7580081 0.92 LMNA (0.30) MEN1KMT2ALMNASMN1; SMN2ALDH1A1
Oxyfluorfen SCHEMBL7576880 0.92 LMNA (0.30) MEN1KMT2ATTRPPOXTDP1
Oxyfluorfen SCHEMBL7586767 0.91 HPD (0.31)
Metolachor SCHEMBL7581970 0.91 TDP1 (0.36) MEN1KMT2ATTRPPOXTDP1
Lactofen SCHEMBL7590677 0.91 TDP1 (0.36) MEN1KMT2ATTRPPOXTDP1
Fomesafen SCHEMBL7586818 0.91 MEN1 (0.36) MEN1KMT2ATTRPPOXTDP1
Oxyfluorfen SCHEMBL7590281 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885KMT2A 2099/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.